We deliver small-scale manufacturing ranging from 100 g-10 kg of innovative intermediate products, with seamless transfer of your project from the bench via our kilo lab to pilot scale.
The first kilogram quantities of expensive intermediates can be delivered flexibly and in a shorter time than with a pilot plant, to support your market launches and ensure success.
Our team collaborates with you to fill-in the missing links from laboratory development to scale-up onto pilot production, enabling you to realize your ambitious project goals.
Guaranteeing punctual delivery of products and services tailored to your requirements allows you to focus your resources elsewhere, while relying on innovative, up-to-date chemical and technical know-how of the highest quality.
We deliver complex, multi-stage chemical synthesis from two production plants located in the Industrial Park Hoechst.
You can leverage our vast experience and skill, backed by flexible, modular equipment in 100 to 5000 liter scale, more than 80 reactors in different materials, and excellent site infrastructure, to maintain an active and competitive long-term position in the marketplace.
Our flexible plant designs facilitate a broad variety of chemical transformations and unit operations. By co-locating development, scale-up and commercial manufacturing, we reduce the cost and time taken to deliver your project. We ensure that scale-up processes and the synthesis of your high-value chemical intermediates are seamlessly managed by our project teams.
We collaborate with you to deliver innovations in process development and synthesis which can be commercialized earlier and over a longer period in the market.
A long track record in the manufacturing of organic electronic materials for:
Organic LED (OLED) for displays
Organic Photovoltaic (OPV)
Organic Photodetector (OPD)
Liquid crystal building blocks in high purity
Materials for batteries
Phosphorus-containing ligands and others (Large commercial and midsize scale)
Metallocenes and homogeneous catalysts
Pilot and midsize plants from 10 kg up to tons scale offering high flexibility
Advanced technologies: Low-temperature, e.g. for boronic acids and high pressure reactions for e.g. chiral compounds
Extended capacities for chemical process development at lab scale for contract research
Process development for applications of bio-based materials
Applied technologies are hydrogenation, oxidation or purifications via rectification or crystallization
Piloting of new products
Manufacturing of test and tox quantities in a range of 100 kg up to tons per campaign
Large scale manufacturing at sites within the WeylChem network
Reactors from 10 to 100 liter constructed of glass, stainless steel and glass-lined steel and other materials as required
Thin film evaporators
Range of filtration units
Heating and cooling system
Vacuum drying cabinets
Option for direct connection to up and downstream units in the pilot plant at 300 to 500 liter
Examples of key technologies used in large scale:
Lithium alanate reduction
Melt reactions at high temperatures
Organometallic reactions, e. g. with BuLi or HexLi
Polymerization or polycondensation
Sodium boro-hydride reduction
Sulfonation (also with oleum)
Advanced reactors with capacities of 100 l, 500 l and 1000 l can be operated via a heating/cooling circuit with an inert heat-transfer medium in the range from -100 °C to +200 °C.
Air-sensitive raw materials (e.g. Grignard-, butyl lithium-, lithium alanate-solutions, etc.) are metered from safety boxes. The reactors are DCS-controlled and equipped with on-site operator terminals. If required, they can quickly be linked to a number of conventional upstream and downstream reactors:
Various specialty chemicals including
Organic boronic acids
Coupled aromatic ring systems
Building blocks for API-synthesis and materials for organic electronic
Reactions including hydroformylations, carbonylations and hydrogenations performed in the presence of catalysts under high pressure to achieve the required conversion, selectivity and yield.
Special high-pressure autoclaves
26 lab autoclaves of 0.2 to 1 liter up to 750 bar, 300 °C in different materials for process development
Piloting: 7 autoclaves from 5 to 300 liter up to 200 bar, 300 °C
Hastelloy up to 1.6 m³ (up to 200 bar, 200 °C)
Stainless steel up to 1.8 m³ (up to 100 bar)
Compressors and gas-supply stations
Ethylene and Hydrogen from pipeline
Pre-formation and handling of air-sensitive homogenous catalysts
Enantiomeric alcohols (e.g. based on ketones)
Carboxylic acid esters and amides
Flexible, variably connectable equipment for complex multi-stage synthesis
Total stirred reactor capacity >50 m3
80 different reaction vessels from 0.1 up to 5.0 m3
Stirred pressure filters up to 4 m2
Thin film evaporators up to 1.0 m2
Short path evaporators up to 0.3 m2
Distillation columns up to 30 theoretical plates
Materials: Stainless steel, glass-lined steel, Hastelloy, glass