The interest in fluorinated compounds is increasing continuously, main application sectors are pharmaceuticals, agrochemicals, polymers, liquid crystals, etc. Normally, the presence of fluorine atoms instead of hydrogens leads to significant different physical and biological properties of the desired product, even chemical reactivity could be strongly influenced by the introduction of fluorine atoms.
Fluconazole is a best selling fluorinated‚ azole type‘ fungicide with much better systemic action and significantly lower dosage rate. Or, gatifloxacin, one of the leading fluoroquinolone antibiotic drugs shows a remarkable commercial success. The ongoing and even increased development of new fluorine containing Life Science molecules is the best indicator, that increased manufacturing costs, due to introduction of fluorine, very much pays off simply getting the better and economical more successful active substance.

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